Molecular Medicine Center

Founded: 1991
Full Time: 80
Part Time:
Budget: 13,614,536.00

Director: Dr. Barbara S. Beckman
Tulane University School of Medicine--Dept. of Pharmacology
1430 Tulane Avenue
New Orleans, LA 70112

Telephone: 504/588-5444 FAX: 504/588-5283
E-Mail: mgerber@tmc.tulane.edu

Research Areas:

Lung Biology, Gene Therapy of Cancer, Drug Resistance, Signal Transduction Mechanisms of Disease, Cardiovascular Disease

Mission:
To promote the application of molecular biology to medical research, in medical education and in molecular diagnosis.

Research Expertise:

Broad based, encompassing all areas of molecular and cellular biology.

Ongoing Projects:

• Molecular diagnosis of human diseases.
• Gene expression in eucaryotic and procaryotic cells.
• Structure and function studies of nucleic acids and proteins.
• Gene thearpy, including basic; animal studies and clinical trials.
• Transgenic animals and disease models.
• Molecular mechanisms of diseases.
• Molecular epidemiology of human diseases.
• Drug design and drug resistance.
• Xenobiotics and environmental informatics.
• Molecular and medical informatics.

Areas of Expertise:

Special Capabilities and Facilities:

• Application of human Genome Project for molecular diagnosis.
• The use of transgenic animals as disease models.
• Pre-clinical gene therapy trials in subhuman primates.
• Drug design using sythetic peptides.
• Informatics, in medicine and in molecular toxicology.
• Structure and Function of RNA and Carbohydrates.
• Gene expression studies in model systems and in human cells.
• Biological response modifiers and signal transduction.
• Viral etiology of human diseases.

Research Equipment:

Flow cytometry, Coulter Epics Elite
ABI 394 DNA/RNA Synthesizer
ABI 270A-HT Capillary Electropheresis System
ABI 477A Pulsed-Liquid Protein Sequencer
ABI 430A Peptide Synthesizer
BIOSYM Tech Molecular Modeling System

Keywords:

0760080, Recombinant DNA;
0710035, biotechnology;
0745020, medical diagnosis;
0710138, medical informatics;
0502024, medical education;
0720005, biomedical research training;
0780010, biomedical research resources;
0780041, transgenic animal;
0755020, disease model;
0745055, preventive medicine;
0765033, pathogenesis;
1002004, celluar biology;
100208, molecular biology;
0745083, gene thearpy;
0725036, environmental medicine;
07101138, cancer biology;
0715008, AIDS